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How to prepare for your baby’s first vaccination

3 September 2025 • Holly Marsh

baby lying down on doctor's bed about to have a vaccination

By Dr Mitsu Shah, Paediatric GP at Kidswell Health

Your baby’s first vaccinations are a big milestone. In the UK, babies are offered their first set of jabs at 8 weeks old, protecting them against serious illnesses such as meningitis, diphtheria, polio, and whooping cough.

For new parents, the idea of that first appointment can feel daunting. Knowing what to expect and how to prepare can make the experience smoother and more reassuring for both you and your baby.

Which vaccinations are given at 8 weeks?

At the first appointment, your baby will usually receive:

  • The 6-in-1 vaccine (protecting against diphtheria, tetanus, whooping cough, polio, Hib, and hepatitis B)
  • The pneumococcal vaccine
  • The rotavirus oral vaccine
  • The MenB vaccine

You can read more about the full schedule in our blog on the updated NHS baby vaccination schedule.

How to prepare for your baby’s vaccination appointment

  1. Bring your Red Book: so the nurse can record your baby’s vaccinations.
  2. Dress your baby in easy-to-remove clothing: quick access to arms and thighs makes the process smoother.
  3. Be ready with infant paracetamol: particularly important after the MenB vaccine, as fever is more common.
  4. Pack a comfort kit: nappies, wipes, a favourite toy or comforter, and milk if bottle-feeding.

Comforting your baby during and after the jabs

  • Hold your baby close: physical comfort helps reduce distress.
  • Breastfeed or bottle-feed during or straight after: Your practitioner may encourage breastfeeding or bottle-feeding during the immunisations for soothing, or immediately afterwards.
  • Skin-to-skin contact: helps regulate your baby’s emotions and body temperature.
  • Offer cuddles and reassurance: most babies settle quickly once they feel safe.

What to expect afterwards

It’s common for babies to:

  • Be irritable or unsettled for a day or two
  • Sleep more than usual
  • Develop a mild fever or soreness at the injection site

To find out more about the side effects head to our blog here.

These side effects are normal and usually short-lived. Give paracetamol if recommended, and keep your baby comfortable with extra cuddles and regular feeds.

Coping as a parent

It’s completely normal to feel anxious too. Many parents find it upsetting to see their baby cry during vaccinations. Remember: the appointment is quick, and nurses are highly skilled at making the process as gentle as possible.

If you’re worried, consider bringing your partner, a friend, or family member for support.

FAQs about your baby’s first vaccination

Do babies feel pain during vaccinations?

Yes, your baby may cry or be briefly upset when the needle goes in. However, the discomfort is very short-lived. Cuddling, breastfeeding, or bottle-feeding straight afterwards helps most babies settle quickly.

Can I give my baby paracetamol before their vaccinations?

It’s not recommended to give paracetamol before the appointment. However, after the MenB vaccine (given at 8 and 16 weeks), NHS guidance advises giving infant paracetamol soon afterwards, as fever is more likely.

What should I do if my baby gets a fever after vaccinations?

A mild fever is common and usually settles within 48 hours. Keep your baby comfortable, offer fluids, and give infant paracetamol if advised. If your baby’s fever goes above 39°C or doesn’t improve, contact your GP or NHS 111.

Can my baby still have their jabs if they have a cold?

If your baby has a mild illness such as a runny nose or cough but no fever, vaccinations can usually go ahead. If they are unwell with a high temperature, your GP or nurse may recommend delaying the appointment.

What happens if we miss the 8-week vaccination appointment?

Don’t worry, your baby can still have their vaccines at a later date. Contact your GP or health visitor as soon as possible to rebook, so your baby doesn’t go unprotected for too long.

Do you offer baby vaccinations at Kidswell Health?

Yes. At Kidswell Health, our paediatric team provides routine vaccinations in a calm, supportive setting. We’re here to answer your questions and make the experience as stress-free as possible.

Final thoughts

Your baby’s first vaccinations are a vital step in protecting them against serious illnesses. By preparing ahead, knowing what to expect, and offering comfort, you can make the experience calmer for both of you.

For more details on the timing and types of baby vaccinations, read our blog on the updated NHS baby vaccination schedule.

At Kidswell Health, our paediatric team is here to answer your questions and support your family through every milestone.

Book a consultation or vaccination with our paediatric specialists

More resources

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